CD276 antibody (C-Term)
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- Target See all CD276 Antibodies
- CD276
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Cow, Pig, Horse, Rabbit, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD276 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VCLIALLVAL AFVCWRKIKQ SCEEENAGAE DQDGEGEGSK TALQPLKHSD
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against CD276. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CD276 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 316 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CD276
- Alternative Name
- CD276 (CD276 Products)
- Synonyms
- sc:d0645 antibody, zgc:158279 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, B7H3 antibody, 4Ig-B7-H3 antibody, B7-H3 antibody, CD276 molecule antibody, CD276 molecule S homeolog antibody, CD276 antigen antibody, Cd276 molecule antibody, CD276 antibody, cd276.S antibody, cd276 antibody, Cd276 antibody
- Background
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The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: B7-H3, B7H3, B7RP-2, 4Ig-B7-H3
Protein Interaction Partner: UBC, RYK,
Protein Size: 316 - Molecular Weight
- 34 kDa
- Gene ID
- 80381
- NCBI Accession
- NM_025240, NP_079516
- Pathways
- Cancer Immune Checkpoints
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