LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (C-Term) antibody

Details for Product No. ABIN2789690, Supplier: Log in to see
Antigen
  • PINCH
  • PINCH-1
  • PINCH1
  • Pinch1
  • RGD1560732
  • LIMS3
  • LIMS3L
  • 2310016J22Rik
  • 4921524A02Rik
  • AI507642
  • AU021743
  • AW551584
  • C430041B13Rik
  • Lims1l
  • LIM and senescent cell antigen-like domains 1
  • LIMS1
  • Lims1
Epitope
C-Term
4
3
3
3
2
1
1
Reactivity
Cow (Bovine), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
53
31
31
4
3
3
3
3
3
3
2
2
2
2
Host
Rabbit
42
12
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
38
19
14
13
9
8
6
5
3
1
1
1
Options
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Available images

Blocking Peptide Blocking peptide for this product available: ABIN979328
Sequence VNCFACSTCN TKLTLKNKFV EFDMKPVCKK CYEKFPLELK KRLKKLAETL
Predicted Reactivity Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against LIMS1. It was validated on Western Blot.
Purification Affinity Purified
Alternative Name LIMS1 (LIMS1 Antibody Abstract)
Background The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PINCH, PINCH1
Protein Interaction Partner: RSU1, UBC, SUMO1, NEDD8, ILK, STUB1, MAPT, MBIP, Hoxa1, HNRNPU, STK11, PARVA, SMURF1, EHMT2, LPXN, NCK2, RBBP8, TMSB4X, TGFBR1, ACP6,
Protein Size: 387
Molecular Weight 44 kDa
Gene ID 3987
NCBI Accession NM_001193485, NP_001180414
UniProt B7Z7R3
Research Area Cancer, Angiogenesis
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 387 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (C-Term) antibody (ABIN2789690) Host: Rabbit
Target Name: LIMS1
Antibody Dilution: 1.0ug/m...