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LIMS1 antibody (C-Term)

LIMS1 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Goat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789690
  • Target See all LIMS1 Antibodies
    LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
    Binding Specificity
    • 15
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 58
    • 23
    • 15
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Goat
    Host
    • 48
    • 10
    Rabbit
    Clonality
    • 48
    • 10
    Polyclonal
    Conjugate
    • 19
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIMS1 antibody is un-conjugated
    Application
    • 18
    • 13
    • 13
    • 13
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    VNCFACSTCN TKLTLKNKFV EFDMKPVCKK CYEKFPLELK KRLKKLAETL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against LIMS1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product LIMS1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 387 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
    Alternative Name
    LIMS1 (LIMS1 Products)
    Synonyms
    PINCH antibody, PINCH-1 antibody, PINCH1 antibody, Pinch1 antibody, RGD1560732 antibody, LIMS3 antibody, LIMS3L antibody, 2310016J22Rik antibody, 4921524A02Rik antibody, AI507642 antibody, AU021743 antibody, AW551584 antibody, C430041B13Rik antibody, Lims1l antibody, LIM zinc finger domain containing 1 antibody, LIM and senescent cell antigen-like domains 1 antibody, LIMS1 antibody, Lims1 antibody
    Background
    The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: PINCH, PINCH1
    Protein Interaction Partner: RSU1, UBC, SUMO1, NEDD8, ILK, STUB1, MAPT, MBIP, Hoxa1, HNRNPU, STK11, PARVA, SMURF1, EHMT2, LPXN, NCK2, RBBP8, TMSB4X, TGFBR1, ACP6,
    Protein Size: 387
    Molecular Weight
    44 kDa
    Gene ID
    3987
    NCBI Accession
    NM_001193485, NP_001180414
    UniProt
    B7Z7R3
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