Endothelin-1 Receptor antibody (C-Term)

Catalog No. ABIN2789694

Product Details anti-Endothelin-1 Receptor Antibody

Target: Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Dog, Horse, Sheep, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endothelin-1 Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KNCFQSCLCC CCYQSKSLMT SVPMNGTSIQ WKNHDQNNHN TDRSSHKDSM

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Sheep: 79%

Characteristics: This is a rabbit polyclonal antibody against EDNRA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 318 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Endothelin-1 Receptor

Target: Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))

Alternative Name: EDNRA (EDNRA Products)

Synonyms: ET-A antibody, ETA antibody, ETA-R antibody, ETAR antibody, ETRA antibody, hET-AR antibody, ET-AR antibody, Endor antibody, Eta antibody, RGD1559432 antibody, ETa antibody, Gpcr10 antibody, ednr-a antibody, ednra antibody, wu:fb75g12 antibody, ednraa antibody, eta antibody, etar antibody, etra antibody, zgc:85942 antibody, endothelin receptor type A antibody, endothelin receptor type Aa antibody, endothelin receptor type A L homeolog antibody, endothelin receptor type Ab antibody, EDNRA antibody, Ednra antibody, ednraa antibody, ednra.L antibody, ednra antibody, ednrab antibody

Background: This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance.
Alias Symbols: ETA, ETAR, ETRA, ET-A, ETA-R, hET-AR
Protein Interaction Partner: VPS11, EDN1, SRC, ARRB2, ARRB1, COPS5, UBC, KAT5, GRK6, GNAI2, GNA11, EDN3, HDAC7,
Protein Size: 318

Molecular Weight: 34 kDa

Gene ID: 1909

NCBI Accession: NM_001166055, NP_001159527

UniProt: P25101

Pathways: cAMP Metabolic Process