Relaxin 2 antibody (C-Term)

Catalog No. ABIN2789762

Product Details anti-Relaxin 2 Antibody

Target: Relaxin 2 (RLN2)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Relaxin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PQLQQHVPVL KDSSLLFEEF KKLIRNRQSE AADSSPSELK YLGLDTHSRK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RLN2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 185 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Relaxin 2

Target: Relaxin 2 (RLN2)

Alternative Name: RLN2 (RLN2 Products)

Synonyms: H2 antibody, H2-RLX antibody, RLXH2 antibody, bA12D24.1.1 antibody, bA12D24.1.2 antibody, RFLX antibody, rln2 antibody, rln3c antibody, rlx3c antibody, si:rp71-39b20.5 antibody, relaxin 2 antibody, insulin-like 3 (Leydig cell) antibody, RLN2 antibody, insl3 antibody

Background: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin.
Alias Symbols: H2, RLXH2, bA12D24.1.1, bA12D24.1.2
Protein Interaction Partner: RXFP2, RXFP1,
Protein Size: 185

Molecular Weight: 21 kDa

Gene ID: 6019

NCBI Accession: NM_134441, NP_604390

UniProt: P04090

Pathways: Hormone Activity