JIP3 antibody (N-Term)

Catalog No. ABIN2789770

Product Details anti-JIP3 Antibody

Target: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JIP3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QYEREKALRR QAEEKFIEFE DALEQEKKEL QIQVEHYEFQ TRQLELKAKN

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Yeast: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against MAPK8IP3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1330 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for JIP3

Target: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Alternative Name: MAPK8IP3 (MAPK8IP3 Products)

Synonyms: JIP3 antibody, JSAP1 antibody, SYD2 antibody, syd antibody, BB120594 antibody, D17Wsu15e antibody, JIP-3 antibody, JSAP1a antibody, JSAP1b antibody, JSAP1c antibody, JSAP1d antibody, Jip3 antibody, Syd2 antibody, mKIAA1066 antibody, mitogen-activated protein kinase 8 interacting protein 3 antibody, MAPK8IP3 antibody, mapk8ip3 antibody, Mapk8ip3 antibody

Background: The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport.
Alias Symbols: DKFZp762N1113, FLJ00027, JIP3, JSAP1, KIAA1066, SYD2, syd
Protein Interaction Partner: MAP2K3, MAP3K5, BCL6, KAT2A, ALK, KLC2, RIC8A, MAPK8IP3, MAPK8IP2, TLR9, MAPK8IP1, TLR4, TLR2, MAP2K7, MAPK10, MAPK9, MAP2K4, MAPK8, PTK2, ARL4D, CASP3, MAP3K11, KLC1, MAP2K1, RAF1, MAP3K1, SRC,
Protein Size: 1330

Molecular Weight: 147 kDa

Gene ID: 23162

NCBI Accession: NM_001040439, NP_001035529

UniProt: E9PFH7