CDK2AP1 antibody (C-Term)

Catalog No. ABIN2789771

Product Details anti-CDK2AP1 Antibody

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK2AP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LLAIIEELGK EIRPTYAGSK SAMERLKRGI IHARGLVREC LAETERNARS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against CDK2AP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CDK2AP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 115 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK2AP1

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Alternative Name: CDK2AP1 (CDK2AP1 Products)

Synonyms: MGC64532 antibody, doc1 antibody, st19 antibody, doc-1 antibody, dorc1 antibody, p12doc-1 antibody, Apc10 antibody, Cdkap1 antibody, DORC1 antibody, Doc1 antibody, ST19 antibody, p12 antibody, DOC1 antibody, p12DOC-1 antibody, cyclin-dependent kinase 2 associated protein 1 S homeolog antibody, cyclin dependent kinase 2 associated protein 1 antibody, cyclin dependent kinase 2 associated protein 1 pseudogene antibody, cyclin-dependent kinase 2 associated protein 1 antibody, CDK2 (cyclin-dependent kinase 2)-associated protein 1 antibody, cdk2ap1.S antibody, CDK2AP1 antibody, LOC475806 antibody, cdk2ap1 antibody, Cdk2ap1 antibody

Background: The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Alias Symbols: DOC1, DORC1, ST19, doc-1, p12DOC-1
Protein Interaction Partner: MRFAP1L1, CCDC136, HDAC2, HDAC1, ZNF420, MTA3, VCP, CDK2AP2, Cebpb, HHV8GK18_gp81, ELAVL1, MBD3, MBD2, RBBP7, RBBP4, SRRM2, POLA1, CDK2, IGHA2, IGHA1, AMY1A,
Protein Size: 115

Molecular Weight: 12 kDa

Gene ID: 8099

NCBI Accession: NM_004642, NP_004633

UniProt: O14519