NDUFS4 antibody (Middle Region)

Catalog No. ABIN2789792

Product Details anti-NDUFS4 Antibody

Target: NDUFS4 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 4, 18kDa (NADH-Coenzyme Q Reductase) (NDUFS4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFS4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FVPARNNMQS GVNNTKKWKM EFDTRERWEN PLMGWASTAD PLSNMVLTFS

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NDUFS4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 175 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDUFS4

Target: NDUFS4 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 4, 18kDa (NADH-Coenzyme Q Reductase) (NDUFS4))

Alternative Name: NDUFS4 (NDUFS4 Products)

Synonyms: 6720411N02Rik antibody, C1-18k antibody, Aqdq antibody, AQDQ antibody, CI-18 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 4 antibody, NADH:ubiquinone oxidoreductase subunit S4 antibody, Ndufs4 antibody, NDUFS4 antibody

Background: This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.
Alias Symbols: AQDQ, CI-18
Protein Interaction Partner: PARK2, UBE2G2, NDUFS7, MARC1, NDUFA12, MRPL15, NDUFAF3, NUP188, TOMM20, UQCRB, RPS2, ABCD3, PRPH, NDUFS6, NDUFB5, MGST3, M6PR, DLAT, CYC1, COX15, CACNA2D1, ATP5O, APP, UBC,
Protein Size: 175

Molecular Weight: 20 kDa

Gene ID: 4724

NCBI Accession: NM_002495, NP_002486

UniProt: O43181