CDC14A antibody (C-Term)

Catalog No. ABIN2789804

Product Details anti-CDC14A Antibody

Target: CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC14A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DDDVEMKNGI TQGDKLRALK SQRQPRTSPS CAFRSDDTKG HPRAVSQPFR

Predicted Reactivity: Cow: 100%, Dog: 87%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CDC14A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 594 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC14A

Target: CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))

Alternative Name: CDC14A (CDC14A Products)

Synonyms: cdc14 antibody, hCDC14 antibody, xcdc14a antibody, A830059A17Rik antibody, CDC14A2 antibody, CDC14a1 antibody, Cdc14 antibody, CDC14A antibody, zgc:63654 antibody, cell division cycle 14A antibody, Dual specificity protein phosphatase CDC14A antibody, dual specificity protein phosphatase CDC14A antibody, cell division cycle 14A L homeolog antibody, CDC14 cell division cycle 14A antibody, cell division cycle 14Aa antibody, CDC14A antibody, TVAG_168700 antibody, TVAG_479730 antibody, TVAG_362610 antibody, TVAG_490830 antibody, GL50803_9270 antibody, CMU_014610 antibody, cdc14a.L antibody, Cdc14a antibody, cdc14a antibody, cdc14aa antibody

Background: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.
Alias Symbols: cdc14, hCDC14
Protein Interaction Partner: CHRM1, CDC6, CDC25B, POLR2A, NPM1, FZR1, TP53, CCNB1, KIF20A, BRAP,
Protein Size: 594

Molecular Weight: 66 kDa

Gene ID: 8556

NCBI Accession: NM_003672, NP_003663

UniProt: Q9UNH5