RCN1 antibody (C-Term)

Catalog No. ABIN2789815

Product Details anti-RCN1 Antibody

Target: RCN1 (Reticulocalbin 1, EF-Hand Calcium Binding Domain (RCN1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCN1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QAEARHLVYE SDKNKDEKLT KEEILENWNM FVGSQATNYG EDLTKNHDEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against RCN1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 331 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RCN1

Target: RCN1 (Reticulocalbin 1, EF-Hand Calcium Binding Domain (RCN1))

Alternative Name: RCN1 (RCN1 Products)

Synonyms: Rcn antibody, PIG20 antibody, RCAL antibody, RCN antibody, reticulocalbin antibody, reticulocalbin 1 antibody, Smp_005230.3 antibody, Rcn1 antibody, RCN1 antibody

Background: Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
Alias Symbols: FLJ37041, PIG20, RCAL, RCN
Protein Interaction Partner: PCSK9, CEP76, HAUS2, CEP250, IRS4, UBC, NEDD8, SUZ12, RNF2, BMI1, EFHD2, CHMP4A, GLRX3, GMPS, TSTA3, IDH1, ENO2, DYRK4, HIPK4, HDAC11, CFTR, ASB8, gag-pol, NOS2, MYC, ILF3, ILF2, TUBA1B, ZYX, SULT1A1, NCL, TOM1L2, SRXN1, LTV1, PPIL3, UFM1, C11orf58, SEC23
Protein Size: 331

Molecular Weight: 39 kDa

Gene ID: 5954

NCBI Accession: NM_002901, NP_002892

UniProt: Q15293