DOC2A antibody (N-Term)

Catalog No. ABIN2789938

Product Details anti-DOC2A Antibody

Target: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOC2A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HCSILRAKGL KPMDFNGLAD PYVKLHLLPG ACKANKLKTK TQRNTLNPVW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DOC2A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 400 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DOC2A

Target: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Alternative Name: DOC2A (DOC2A Products)

Synonyms: DOC2A antibody, doc2-A antibody, Doc2 antibody, double C2 domain alpha antibody, double C2-like domains, alpha antibody, double C2, alpha antibody, DOC2A antibody, doc2a antibody, Doc2a antibody

Background: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes, these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.
Alias Symbols: Doc2
Protein Interaction Partner: UBASH3B, RAP1GDS1, DYNLT1, UNC13B, STXBP1,
Protein Size: 400

Molecular Weight: 44 kDa

Gene ID: 8448

NCBI Accession: NM_003586, NP_003577

UniProt: Q14183

Pathways: Synaptic Vesicle Exocytosis