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TXNRD3 antibody (Middle Region)

TXNRD3 Reactivity: Human, Mouse, Rabbit, Dog, Guinea Pig, Horse, Pig, Rat, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789949
  • Target See all TXNRD3 Antibodies
    TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))
    Binding Specificity
    • 7
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rabbit, Dog, Guinea Pig, Horse, Pig, Rat, Zebrafish (Danio rerio)
    Host
    • 11
    Rabbit
    Clonality
    • 11
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXNRD3 antibody is un-conjugated
    Application
    • 11
    • 7
    • 1
    Western Blotting (WB)
    Sequence
    NHISSLNWGY RLSLREKAVA YVNSYGEFVE HHKIKATNKK GQETYYTAAQ
    Predicted Reactivity
    Dog: 86%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 85%, Rat: 79%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against TXNRD3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product TXNRD3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 607 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))
    Alternative Name
    TXNRD3 (TXNRD3 Products)
    Synonyms
    MGC81848 antibody, MGC147163 antibody, TGR antibody, TR2 antibody, TRXR3 antibody, AI196535 antibody, Tgr antibody, thioredoxin reductase 3 antibody, apoptosis-inducing factor 3 antibody, thioredoxin reductase 3 L homeolog antibody, TXNRD3 antibody, LOC413958 antibody, txnrd3.L antibody, txnrd3 antibody, Txnrd3 antibody
    Background
    This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: TGR, TR2, TRXR3
    Protein Interaction Partner: UBC,
    Protein Size: 607
    Molecular Weight
    66 kDa
    Gene ID
    114112
    NCBI Accession
    NM_001173513, NP_001166984
    UniProt
    Q86VQ6
    Pathways
    Cell RedoxHomeostasis
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