BMP8A antibody (Middle Region)

Catalog No. ABIN2789951

Product Details anti-BMP8A Antibody

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP8A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VRPLRRRQPK KTNELPQANR LPGIFDDVHG SHGRQVCRRH ELYVSFQDLG

Predicted Reactivity: Dog: 83%, Guinea Pig: 83%, Horse: 75%, Human: 100%, Mouse: 83%, Rabbit: 83%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against BMP8A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BMP8B

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMP8A

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Alternative Name: BMP8A (BMP8A Products)

Synonyms: Bmp7r1 antibody, OP-2 antibody, OP2 antibody, bmp8 antibody, bone morphogenetic protein 8a antibody, Bmp8a antibody, BMP8A antibody, bmp8a antibody

Background: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.
Alias Symbols: OP2, BMP8
Protein Size: 238

Molecular Weight: 26 kDa

Gene ID: 656

NCBI Accession: NM_001720, NP_001711

UniProt: P34820

Pathways: Negative Regulation of Hormone Secretion