EI24 antibody (N-Term)

Catalog No. ABIN2790002

Product Details anti-EI24 Antibody

Target: EI24 (Etoposide Induced 2.4 (EI24))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EI24 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ICTISKLDAR IQQKREEQRR RRASSVLAQR RAQSIERKQE SEPRIVSRIF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against EI24. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 262 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EI24

Target: EI24 (Etoposide Induced 2.4 (EI24))

Alternative Name: EI24 (EI24 Products)

Synonyms: EPG4 antibody, PIG8 antibody, TP53I8 antibody, AA536736 antibody, AI115355 antibody, EI24, autophagy associated transmembrane protein antibody, etoposide induced 2.4 mRNA antibody, EI24 antibody, Ei24 antibody

Background: This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: PIG8, TP53I8
Protein Interaction Partner: UBC,
Protein Size: 262

Molecular Weight: 30 kDa

Gene ID: 9538

NCBI Accession: NM_001007277, NP_001007278

UniProt: O14681