PHAX antibody (C-Term)

Catalog No. ABIN2790158

Product Details anti-PHAX Antibody

Target: PHAX (phosphorylated Adaptor For RNA Export (PHAX))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHAX antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DIFYIENQKE YENKKAARKR RTQVLGKKMK QAIKSLNFQE DDDTSRETFA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PHAX. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHAX

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 394 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHAX

Target: PHAX (phosphorylated Adaptor For RNA Export (PHAX))

Alternative Name: PHAX (PHAX Products)

Synonyms: RNUXA antibody, 2810055C14Rik antibody, 4933427L19Rik antibody, AU018701 antibody, AU018854 antibody, D18Ertd65e antibody, Rnuxa antibody, p55 antibody, phosphorylated adaptor for RNA export antibody, PHAX antibody, Phax antibody

Background: PHAX is a phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. PHAX is also a bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other.
Alias Symbols: FLJ13193, RNUXA
Protein Interaction Partner: CIAO1, UBC, LIN28B, LIN28A, ZNF346, HSP90B1, CALD1, SNORD13P1, SNORD118, LOC366310, PAXIP1, EIF4B, CAND1, CUL3, SUMO2, ZWINT, GADD45G, TNFSF11, MKNK1, VAV1, STK3, RPS6KA1, RAD23A, PDPK1, GRB7, UBXN2A, ASPSCR1, NSFL1C, XPO1, SNORD3A,
Protein Size: 394

Molecular Weight: 44 kDa

Gene ID: 51808

NCBI Accession: NM_032177, NP_115553

UniProt: Q9H814

Pathways: Ribonucleoprotein Complex Subunit Organization