PHAX antibody (Middle Region)

Catalog No. ABIN2790159

Product Details anti-PHAX Antibody

Target: PHAX (phosphorylated Adaptor For RNA Export (PHAX))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHAX antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NYLLAKKLRK ESQEHTKDLD KELDEYMHGG KKMGSKEEEN GQGHLKRKRP

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 75%, Horse: 92%, Human: 100%, Mouse: 77%, Pig: 83%, Rabbit: 79%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against PHAX. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PHAX

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHAX

Target: PHAX (phosphorylated Adaptor For RNA Export (PHAX))

Alternative Name: PHAX (PHAX Products)

Background: PHAX is a phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. PHAX is also a bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other.
Alias Symbols: RNUXA
Protein Interaction Partner: CIAO1, UBC, LIN28B, LIN28A, ZNF346, HSP90B1, CALD1, SNORD13P1, SNORD118, LOC366310, PAXIP1, EIF4B, CAND1, CUL3, SUMO2, ZWINT, GADD45G, TNFSF11, MKNK1, VAV1, STK3, RPS6KA1, RAD23A, PDPK1, GRB7, UBXN2A, ASPSCR1, NSFL1C, XPO1, SNORD3A,
Protein Size: 394

Molecular Weight: 44 kDa

Gene ID: 51808

NCBI Accession: NM_032177, NP_115553

UniProt: Q9H814

Pathways: Ribonucleoprotein Complex Subunit Organization