LIMS2 antibody (N-Term)

Catalog No. ABIN2790264

Product Details anti-LIMS2 Antibody

Target: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Binding Specificity: N-Term

Reactivity: Mouse, Human, Rat, Cow, Dog, Horse, Pig, Rabbit, Goat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIMS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DVELADLGFV KNAGRHLCRP CHNREKAKGL GKYICQRCHL VIDEQPLMFR

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against LIMS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LIMS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 336 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIMS2

Target: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Alternative Name: LIMS2 (LIMS2 Products)

Background: This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ10044, PINCH2, PINCH-2
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-5, KRTAP10-7, KRT40, RCHY1, MTUS2, CALCOCO2, MDFI, GOLGA2, SUMO2, ILK, HIPK3, APP,
Protein Size: 336

Molecular Weight: 38 kDa

Gene ID: 55679

NCBI Accession: NM_001161404, NP_001154876

UniProt: Q7Z4I7

Pathways: Cell-Cell Junction Organization