TMBIM4 antibody (Middle Region)

Catalog No. ABIN2790594

Product Details anti-TMBIM4 Antibody

Target: TMBIM4 (Transmembrane BAX Inhibitor Motif Containing 4 (TMBIM4))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMBIM4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LTVAVVVTFY DVYIILQAFI LTTTVFFGLT VYTLQSKKDF SKFGAGLFAL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TMBIM4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human TMBIM4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 258 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMBIM4

Target: TMBIM4 (Transmembrane BAX Inhibitor Motif Containing 4 (TMBIM4))

Alternative Name: TMBIM4 (TMBIM4 Products)

Synonyms: GAAP antibody, LFG4 antibody, S1R antibody, ZPRO antibody, Cgi119 antibody, 0610007H07Rik antibody, AU022431 antibody, transmembrane BAX inhibitor motif containing 4 antibody, TMBIM4 antibody, Tmbim4 antibody

Background: TMBIM4 is an anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. It can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release.
Alias Symbols: CGI-119, GAAP, S1R, ZPRO, LFG4
Protein Interaction Partner: VKORC1, CCDC47, SLC27A4, RPN2, PRPSAP1, PPIB, MTX1, DFFA, DDOST, COX4I1,
Protein Size: 258

Molecular Weight: 28 kDa

Gene ID: 51643

NCBI Accession: NM_016056, NP_057140

UniProt: Q9HC24