PPP1R9A antibody (N-Term)

Catalog No. ABIN2790677

Product Details anti-PPP1R9A Antibody

Target: PPP1R9A (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 9A (PPP1R9A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R9A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GERTTLRSAS PHRNAYRTEF QALKSTFDKP KSDGEQKTKE GEGSQQSRGR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PPP1R9A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PPP1R9A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1374 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PPP1R9A antibody (ABIN2790677)

Montesinos-Rongen, Terrao, May, Marcus, Blümcke, Hellmich, Küppers, Brunn, Deckert: "The process of somatic hypermutation increases polyreactivity for central nervous system antigens in primary central nervous system lymphoma." in: Haematologica, (2020) (PubMed).

Target Details for PPP1R9A

Target: PPP1R9A (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 9A (PPP1R9A))

Alternative Name: PPP1R9A (PPP1R9A Products)

Synonyms: 2810430P21Rik antibody, 4930518N04Rik antibody, 5330407E15 antibody, A230094E16Rik antibody, BB181831 antibody, NRB antibody, mKIAA1222 antibody, neurabin-I antibody, NRB1 antibody, NRBI antibody, Neurabin-I antibody, Neb1 antibody, protein phosphatase 1, regulatory (inhibitor) subunit 9A antibody, protein phosphatase 1 regulatory subunit 9A antibody, protein phosphatase 1, regulatory subunit 9A antibody, Ppp1r9a antibody, PPP1R9A antibody

Background: This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ20068, KIAA1222, NRB1, NRBI, Neurabin-I
Protein Interaction Partner: ANKRD28, UBC, WDR48, PPP1R9A, PPP1CA, RPS6KB1, PPP1R9B, TGOLN2, PPP1R2, PRKAR1B, ACTG1,
Protein Size: 1374

Molecular Weight: 151 kDa

Gene ID: 55607

NCBI Accession: NM_001166160, NP_001159632

UniProt: B2RWQ1