ALG10B antibody (N-Term)

Catalog No. ABIN2790718

Product Details anti-ALG10B Antibody

Target: ALG10B (Asparagine-Linked Glycosylation 10, alpha-1,2-Glucosyltransferase Homolog B (ALG10B))

Binding Specificity: N-Term

Reactivity: Human, Dog, Horse, Rat, Guinea Pig, Mouse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALG10B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SVGNFYLLYL LFHKVQPRNK AASSIQRVLS TLTLAVFPTL YFFNFLYYTE

Predicted Reactivity: Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ALG10B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ALG10B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 473 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALG10B

Target: ALG10B (Asparagine-Linked Glycosylation 10, alpha-1,2-Glucosyltransferase Homolog B (ALG10B))

Alternative Name: ALG10B (ALG10B Products)

Synonyms: ALG10 antibody, KCR1 antibody, AA469671 antibody, AU045404 antibody, AW123895 antibody, C85569 antibody, Deaf1 antibody, Gm917 antibody, nse5 antibody, ALG10B, alpha-1,2-glucosyltransferase antibody, asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase) antibody, ALG10B antibody, Alg10b antibody

Background: ALG10B is a putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. ALG10B transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.
Alias Symbols: ALG10, KCR1
Protein Interaction Partner: UBC, KCNH2,
Protein Size: 473

Molecular Weight: 55 kDa

Gene ID: 144245

NCBI Accession: NM_001013620, NP_001013642

UniProt: Q5I7T1