IQSEC2 antibody (Middle Region)

Catalog No. ABIN2790791

Product Details anti-IQSEC2 Antibody

Target: IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))

Binding Specificity: Middle Region

Reactivity: Mouse, Human, Rat, Rabbit, Cow, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQSEC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ARTIQTAFRQ YRMNKNFERL RSSASESRMS RRIILSNMRM QFSFEEYEKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against IQSEC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human IQSEC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1488 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IQSEC2

Target: IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))

Alternative Name: IQSEC2 (IQSEC2 Products)

Synonyms: BRAG1 antibody, MRX1 antibody, Brag1 antibody, mKIAA0522 antibody, RGD1562109 antibody, IQ motif and Sec7 domain 2 antibody, IQSEC2 antibody, Iqsec2 antibody

Background: This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation.
Alias Symbols: BRAG1, KIAA0522
Protein Interaction Partner: UBC, ELAVL1,
Protein Size: 1488

Molecular Weight: 163 kDa

Gene ID: 23096

NCBI Accession: NM_001111125, NP_001104595