YARS2 antibody (C-Term)

Catalog No. ABIN2790888

Product Details anti-YARS2 Antibody

Target: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YARS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QPDDSVERYL KLFTFLPLPE IDHIMQLHVK EPERRGPQKR LAAEVTKLVH

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against YARS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human YARS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 477 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YARS2

Target: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Alternative Name: YARS2 (YARS2 Products)

Synonyms: 2210023C10Rik antibody, tyrRS antibody, CGI-04 antibody, RGD1311696 antibody, MLASA2 antibody, MT-TYRRS antibody, TYRRS antibody, tyrosyl-tRNA synthetase 2 (mitochondrial) antibody, tyrosyl-tRNA synthetase 2 antibody, Yars2 antibody, YARS2 antibody

Background: This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2).
Alias Symbols: MLASA2, MT-TYRRS, TYRRS
Protein Interaction Partner: FAM9B, UBC, BMI1, DDRGK1, CAND1, CUL3, Ybx1, ICT1, USP49, CDC20,
Protein Size: 477

Molecular Weight: 52 kDa

Gene ID: 51067

NCBI Accession: NM_001040436, NP_001035526

UniProt: Q9Y2Z4