PARPBP antibody (C-Term)

Catalog No. ABIN2790948

Product Details anti-PARPBP Antibody

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Binding Specificity: C-Term

Reactivity: Human, Horse, Rabbit, Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARPBP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YMENDLSEGV NPSVGRSTIG TSFGNVHLDR SKNEKVSRKS TSQTGNKSSK

Predicted Reactivity: Horse: 85%, Human: 100%, Pig: 92%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PARPBP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PARPBP

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Alternative Name: PARPBP (PARPBP Products)

Synonyms: C12orf48 antibody, PARI antibody, PARPBP antibody, AROM antibody, C5H12orf48 antibody, PARP1BP antibody, si:ch211-260p3.2 antibody, zgc:136263 antibody, c12orf48 antibody, 4930547N16Rik antibody, AI503644 antibody, PARP1 binding protein antibody, PARP1 binding protein L homeolog antibody, PARPBP antibody, Parpbp antibody, parpbp antibody, parpbp.L antibody

Background: PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. PARPBP antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly(A) homopolymers and positively regulate the poly(ADP-ribosyl)ation activity of PARP1, however such function may be indirect.
Protein Interaction Partner: UBC,
Protein Size: 294

Molecular Weight: 32 kDa

Gene ID: 55010