AP4B1 antibody (C-Term)

Catalog No. ABIN2791064

Product Details anti-AP4B1 Antibody

Target: AP4B1 (Adaptor-Related Protein Complex 4, beta 1 Subunit (AP4B1))

Binding Specificity: C-Term

Reactivity: Human, Rabbit, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP4B1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GAERCDPELP KTSSFAASGP LIPEENKERV QELPDSGALM LVPNRQLTAD

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against AP4B1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human AP4B1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AP4B1

Target: AP4B1 (Adaptor-Related Protein Complex 4, beta 1 Subunit (AP4B1))

Alternative Name: AP4B1 (AP4B1 Products)

Synonyms: AP4B1 antibody, DDBDRAFT_0185456 antibody, DDBDRAFT_0234245 antibody, DDB_0185456 antibody, DDB_0234245 antibody, BETA-4 antibody, CPSQ5 antibody, SPG47 antibody, 1810038H16Rik antibody, AV004952 antibody, Ap4b4 antibody, adaptor related protein complex 4 beta 1 subunit antibody, adaptor-related protein complex 4, beta 1 subunit antibody, adaptor-related protein complex AP-4, beta 1 antibody, AP4B1 antibody, ap4b1 antibody, Ap4b1 antibody

Background: This gene encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CPSQ5, SPG47, BETA-4
Protein Size: 571

Molecular Weight: 62 kDa

Gene ID: 10717

NCBI Accession: NM_001308312, NP_001295241

UniProt: B1ALD0