MRPL14 antibody (C-Term)

Catalog No. ABIN2791154

Product Details anti-MRPL14 Antibody

Target: MRPL14 (Mitochondrial Ribosomal Protein L14 (MRPL14))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Goat, Horse, Pig, Zebrafish (Danio rerio), Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL14 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MTPRFDSNNV VLIEDNGNPV GTRIKTPIPT SLRKREGEYS KVLAIAQNFV

Predicted Reactivity: Cow: 86%, Dog: 86%, Goat: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 79%, Rat: 93%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against MRPL14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRPL14

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL14

Target: MRPL14 (Mitochondrial Ribosomal Protein L14 (MRPL14))

Alternative Name: MRPL14 (MRPL14 Products)

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 17p13.3.
Alias Symbols: L14mt, L32mt, MRP-L14, MRP-L32, MRPL32, RMPL32, RPML32
Protein Interaction Partner: RPS20, NDUFA7, MRPL53, GADD45GIP1, SARNP, MRPL38, MRPL40, MRPS14, SRPRB, CDV3, MRPS10, MRPL16, MRPL39, MRPL4, MRPL2, MRPL22, MRPL15, MRPL13, HNRNPR, PPIF, MRPL19, EEF1A1, DUT, TUFM, CUL3, UBC, ICT1,
Protein Size: 145

Molecular Weight: 15 kDa

Gene ID: 64928

NCBI Accession: NM_032111, NP_115487

UniProt: Q6P1L8