NUF2 antibody (N-Term)

Catalog No. ABIN2792062

Product Details anti-NUF2 Antibody

Target: NUF2 (NUF2, NDC80 Kinetochore Complex Component (NUF2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EIVIHIRNKI LTGADGKNLT KNDLYPNPKP EVLHMIYMRA LQIVYGIRLE

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NUF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human NUF2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NUF2

Target: NUF2 (NUF2, NDC80 Kinetochore Complex Component (NUF2))

Alternative Name: NUF2 (NUF2 Products)

Synonyms: 2410003C07Rik antibody, AU044112 antibody, C85691 antibody, Cdca1 antibody, NUF2R antibody, CDCA1 antibody, CT106 antibody, zgc:56708 antibody, cdca1 antibody, ct106 antibody, nuf2 antibody, nuf2-a antibody, nuf2-b antibody, nuf2r antibody, xNuf2 antibody, cdca1-B antibody, xnuf2 antibody, NUF2, NDC80 kinetochore complex component antibody, NUF2, NDC80 kinetochore complex component, homolog antibody, spindle pole body protein Nuf2 antibody, NUF2, NDC80 kinetochore complex component L homeolog antibody, NUF2, NDC80 kinetochore complex component S homeolog antibody, Nuf2 antibody, NUF2 antibody, nuf2 antibody, nuf2.L antibody, nuf2.S antibody

Background: This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described.
Alias Symbols: CDCA1, CT106, NUF2R
Protein Size: 417

Molecular Weight: 45 kDa

Gene ID: 83540

NCBI Accession: NM_031423, NP_113611

UniProt: Q9BZD4

Pathways: Maintenance of Protein Location