CCL8 antibody (Middle Region)

Catalog No. ABIN2792194

Product Details anti-CCL8 Antibody

Target: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SYTRITNIQC PKEAVIFKTK RGKEVCADPK ERWVRDSMKH LDQIFQNLKP

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CCL8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCL8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 99 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCL8

Target: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Alternative Name: CCL8 (CCL8 Products)

Synonyms: HC14 antibody, MCP-2 antibody, MCP2 antibody, SCYA10 antibody, SCYA8 antibody, 1810063B20Rik antibody, AB023418 antibody, Mcp2 antibody, Scya8 antibody, C-C motif chemokine ligand 8 antibody, chemokine (C-C motif) ligand 8 antibody, C-C motif chemokine 8 antibody, monocyte chemoattractant protein-2 precursor antibody, CCL8 antibody, Ccl8 antibody, LOC101119572 antibody, MCP-2 antibody

Background: CCL8 gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HC14, MCP-2, MCP2, SCYA10, SCYA8
Protein Interaction Partner: ACKR2, ACKR4, CCR5, CCR3, CCR2, CCR1, MMP3, VCAN, ACKR1,
Protein Size: 99

Molecular Weight: 9 kDa

Gene ID: 6355

NCBI Accession: NM_005623, NP_005614

UniProt: P80075