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TRAF4 antibody (Middle Region)

TRAF4 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2792211
  • Target See all TRAF4 Antibodies
    TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))
    Binding Specificity
    • 10
    • 9
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 55
    • 19
    • 10
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 52
    • 3
    Rabbit
    Clonality
    • 53
    • 2
    Polyclonal
    Conjugate
    • 31
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TRAF4 antibody is un-conjugated
    Application
    • 36
    • 22
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LEAPGGWLDH SNTSLGINTP VNGSPVCLEA WDPASAGPAR FSLSLLLFFL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TRAF4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TRAF4
    Top Product
    Discover our top product TRAF4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 470 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))
    Alternative Name
    TRAF4 (TRAF4 Products)
    Synonyms
    CART1 antibody, MLN62 antibody, RNF83 antibody, A530032M13Rik antibody, msp2 antibody, traf4 antibody, cart1 antibody, mln62 antibody, rnf83 antibody, traf-4 antibody, traf4l antibody, zgc:77418 antibody, TNF receptor associated factor 4 antibody, Tnf receptor associated factor 4 antibody, tnf receptor-associated factor 4b antibody, TNF receptor associated factor 4 L homeolog antibody, tnf receptor-associated factor 4a antibody, TRAF4 antibody, Traf4 antibody, traf4b antibody, traf4.L antibody, traf4a antibody
    Background
    TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CART1, MLN62, RNF83
    Protein Interaction Partner: HOMEZ, BYSL, REXO1L6P, PKD1P1, KANSL1, BCL6B, UBL4B, KRT40, FBXL18, BANP, SPDL1, ALKBH4, WBP11, ZNF581, ISYNA1, TBC1D7, GORASP2, EXOC7, BAHD1, WWP2, WWP1, MRPL28, NOS1AP, TRAF4, UBL4A, ZNF3, SUMO1, UBC, TYK2, TP53BP2, QARS, KRT31, ARNT2, TRAF2, USP15, TGF
    Protein Size: 470
    Molecular Weight
    53 kDa
    Gene ID
    9618
    NCBI Accession
    NM_004295, NP_004286
    UniProt
    Q9BUZ4
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