RGS5 antibody (Middle Region)

Catalog No. ABIN2792216

Product Details anti-RGS5 Antibody

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PDSVGDLVIP YNEKPEKPAK TQKTSLDEAL QWRDSLDKLL QNNYGLASFK S

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 84%, Pig: 76%, Rat: 84%

Characteristics: This is a rabbit polyclonal antibody against RGS5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RGS5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 181 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS5

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Alternative Name: RGS5 (RGS5 Products)

Synonyms: MST092 antibody, MST106 antibody, MST129 antibody, MSTP032 antibody, MSTP092 antibody, MSTP106 antibody, MSTP129 antibody, RGS5 antibody, 1110070A02Rik antibody, fj30h05 antibody, rgs5 antibody, wu:fj30h05 antibody, zgc:64006 antibody, xrgs5 antibody, MGC147439 antibody, zgc:110206 antibody, regulator of G protein signaling 5 antibody, regulator of G-protein signaling 5 antibody, regulator of G protein signaling 5a antibody, regulator of G-protein signaling 5 L homeolog antibody, regulator of G protein signaling 5b antibody, RGS5 antibody, Rgs5 antibody, rgs5a antibody, rgs5 antibody, rgs5.L antibody, rgs5b antibody

Background: The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-663 AU130764.1 1-663 664-2587 BX537427.1 499-2422 2588-3235 BU187973.1 34-681 3236-3746 AL600981.1 90-600 3747-4143 AA486366.1 76-472 4144-4358 AA974387.1 113-327 c 4359-4664 BX537427.1 4194-4499 4665-5573 AF176919.1 724-1632 5574-5848 BX537427.1 5409-5683
Alias Symbols: MST092, MST106, MST129, MSTP032, MSTP092, MSTP106, MSTP129
Protein Interaction Partner: ADRB2, APP, GNAQ, GNAI3, GNAI2, GNAO1, GNAI1,
Protein Size: 181

Molecular Weight: 21 kDa

Gene ID: 8490

NCBI Accession: NM_003617, NP_003608

UniProt: O15539

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling