SRP72 antibody (Middle Region)

Catalog No. ABIN2792227

Product Details anti-SRP72 Antibody

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Zebrafish (Danio rerio), Cow, Rat, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRP72 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GDSQPKEQGQ GDLKKKKKKK KGKLPKNYDP KVTPDPERWL PMRERSYYRG

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 80%

Characteristics: This is a rabbit polyclonal antibody against SRP72. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRP72

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 671 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRP72

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Alternative Name: SRP72 (SRP72 Products)

Synonyms: CG5434 antibody, Dmel\\CG5434 antibody, wu:fi03d11 antibody, 5730576P14Rik antibody, 72kDa antibody, AI132477 antibody, BC019196 antibody, C77589 antibody, BMFF antibody, Signal recognition particle protein 72 antibody, signal recognition particle 72 antibody, signal recognition particle 72kDa antibody, signal recognition particle subunit Srp72 (predicted) antibody, part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex antibody, type II secretory pathway family antibody, signal recognition particle 72kDa S homeolog antibody, Srp72 antibody, SRP72 antibody, srp72 antibody, srp72.S antibody

Background: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP72 binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
Alias Symbols: BMFF
Protein Interaction Partner: STAU1, LIN28A, TARBP2, RNF2, KIF21A, MLF2, SOX2, METTL18, UBC, SKIL, SRP68, CAND1, CUL3, SIRT7, FCHSD2, HDGF, MEPCE, RPAP1, HNRNPA1, CASP6, CASP3,
Protein Size: 671

Molecular Weight: 74 kDa

Gene ID: 6731

NCBI Accession: NM_006947, NP_008878

UniProt: O76094

Pathways: SARS-CoV-2 Protein Interactome