HTR7 antibody (N-Term)

Catalog No. ABIN2792278

Product Details anti-HTR7 Antibody

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HLLSEVTASP APTWDAPPDN ASGCGEQINY GRVEKVVIGS ILTLITLLTI

Predicted Reactivity: Dog: 100%, Horse: 85%, Human: 100%, Mouse: 92%, Pig: 85%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against HTR7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 445 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HTR7

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Alternative Name: HTR7 (HTR7 Products)

Synonyms: 5-HT7 antibody, 5-HT-dro antibody, 5-HT-dro1 antibody, 5-HT7Dro antibody, 5-HT[7]Dro antibody, 5-HT[[7Dro]] antibody, 5-HT[[7]] antibody, 5-HT[[7]]Dro antibody, 5-HT[[dro1]] antibody, 5-HTdro1 antibody, 5HT-7 antibody, 5HT-R1 antibody, 5HT-dro antibody, 5HT-dro1 antibody, 5HT[[7Dro]] antibody, 5htdror antibody, CG12073 antibody, DRO1 antibody, Dm5HTdro1 antibody, Dmel\\CG12073 antibody, 5Ht7 antibody, 5HT7 antibody, htr7-A antibody, 5-hydroxytryptamine receptor 7 antibody, 5-hydroxytryptamine (serotonin) receptor 7 antibody, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled antibody, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled L homeolog antibody, HTR7 antibody, 5-HT7 antibody, LOC752003 antibody, Htr7 antibody, htr7.L antibody

Background: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by g proteins that stimulate adenylate cyclase.
Alias Symbols: 5-HT7
Protein Interaction Partner: GPRASP2, GPRASP1, RHOBTB3, CUL3,
Protein Size: 445

Molecular Weight: 49 kDa

Gene ID: 3363

NCBI Accession: NM_000872, NP_000863

UniProt: P34969

Pathways: JAK-STAT Signaling