Glucocorticoid Receptor antibody (N-Term)

Catalog No. ABIN2792573

Product Details anti-Glucocorticoid Receptor Antibody

Target: Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucocorticoid Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDSKESLTPG REENPSSVLA QERGDVMDFY KTLRGGATVK VSASSPSLAV

Cross-Reactivity: Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)

Predicted Reactivity: Human: 100%, Mouse: 78%, Pig: 78%, Rabbit: 85%, Rat: 78%

Characteristics: This is a rabbit polyclonal antibody against NR3C1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NR3C1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Antigen size: 777 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Glucocorticoid Receptor antibody (ABIN2792573)

"Triazolam Effects On Explicit Memory, Implicit Memory and Metamemory: Lister RG, Joyce EM, Weingartner HJ, Eckardt MJ Laboratory of Clinical Studies, NIAAA, DICBR, Bldg 10 Rm 3C102, 9000 Rockville Pike, Bethesda, MD 20892, USA." in: Journal of psychopharmacology (Oxford, England), Vol. 6, Issue 1, pp. 133, (2012) (PubMed).

Target Details for Glucocorticoid Receptor

Target: Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))

Alternative Name: Glucocorticoid receptor (NR3C1 Products)

Synonyms: GR antibody, gcr antibody, grl antibody, xGR antibody, gccr antibody, gr antibody, zgc:113038 antibody, NR3C1 antibody, GCL antibody, LOC100302444 antibody, Gcr antibody, Grl antibody, Grl-1 antibody, Grl1 antibody, GRL antibody, GCCR antibody, GCR antibody, NO antibody, GR-A antibody, nr3c1 antibody, nuclear receptor subfamily 3 group C member 1 antibody, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antibody, nuclear receptor subfamily 3, group C, member 1 antibody, glucocorticoid receptor antibody, NR3C1 antibody, nr3c1 antibody, LOC100302444 antibody, Nr3c1 antibody

Background: Glucocorticoid receptor beta
Alias Symbols: GCCR, GCR, GR, GRL
Protein Interaction Partner: TTC5, HSP90AA1, TXN2, UBC, TXN, FKBP5, DCAF6, RABEP2, BRCC3, LARP7, GAPVD1, CD2AP, SF3A1, HNRNPR, TRIM28, HDAC1, MTA2, CCDC6, CENPB, TMF1, PPARG, STUB1, BAG1, RPS6KA5, NCOA1, POLR1D, NCOA2, SRA1, PRKDC, RAD54L2, MAGEA11, PPP5C, PPID, GNB2, GNB1, FKBP4, GN
Protein Size: 777

Molecular Weight: 86 kDa

Gene ID: 2908

NCBI Accession: NM_000176, NP_000167

UniProt: P04150

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process