ELK3 antibody (Middle Region)

Catalog No. ABIN2792616

Product Details anti-ELK3 Antibody

Target: ELK3 (ELK3, ETS-Domain Protein (SRF Accessory Protein 2) (ELK3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELK3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RTVIRFVTNK TDKHVTRPVV SLPSTSEAAA ASAFLASSVS AKISSLMLPN

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 92%, Dog: 84%, Guinea Pig: 78%, Horse: 78%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against ELK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ELK3

Application Details

Application Notes: WB Suggested Anti-ELK3 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:12500
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 407 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ELK3

Target: ELK3 (ELK3, ETS-Domain Protein (SRF Accessory Protein 2) (ELK3))

Alternative Name: ELK3 (ELK3 Products)

Synonyms: D430049E23Rik antibody, Erp antibody, Etrp antibody, Net antibody, Sap-2 antibody, erp antibody, sap2 antibody, ERP antibody, NET antibody, SAP2 antibody, si:ch211-172b12.2 antibody, si:dkey-201e17.1 antibody, zgc:198153 antibody, zgc:198183 antibody, ELK3, member of ETS oncogene family antibody, ELK3, ETS transcription factor L homeolog antibody, ELK3, ETS transcription factor antibody, ELK3, ETS-domain protein antibody, Elk3 antibody, elk3.L antibody, ELK3 antibody, elk3 antibody

Background: ELK3 is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. ELK3 is activated by signal-induced phosphorylation, studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation, studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-619 Z36715.1 1-619 620-2180 BC017371.1 549-2109
Alias Symbols: ERP, NET, SAP2
Protein Interaction Partner: APP, TOP1, UBC, PIAS1, MAPK9, CTBP1, MAPK8, ID2, MAPK14, TCF3,
Protein Size: 407

Molecular Weight: 44 kDa

Gene ID: 2004

NCBI Accession: NM_005230, NP_005221

UniProt: P41970