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TFAP2A antibody (C-Term)

TFAP2A Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2792629
  • Target See all TFAP2A Antibodies
    TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
    Binding Specificity
    • 10
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 55
    • 19
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Guinea Pig, Rabbit
    Host
    • 38
    • 17
    • 3
    Rabbit
    Clonality
    • 40
    • 18
    Polyclonal
    Conjugate
    • 34
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TFAP2A antibody is un-conjugated
    Application
    • 43
    • 29
    • 11
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    NLISHGFGSP AVCAAVTALQ NYLTEALKAM DKMYLSNNPN SHTDNNAKSS
    Cross-Reactivity
    Cow (Bovine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
    Predicted Reactivity
    Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
    Characteristics
    This is a rabbit polyclonal antibody against TFAP2A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human TFAP2A
    Top Product
    Discover our top product TFAP2A Primary Antibody
  • Application Notes
    WB Suggested Anti-TFAP2A Antibody Titration: 1.25 µg/mL
    ELISA Titer: 1:312500
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 437 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
    Alternative Name
    AP-2 alpha / TFAP2A (TFAP2A Products)
    Synonyms
    TFAP2A antibody, Ap-2 antibody, AP-2 antibody, AP-2alpha antibody, AP2TF antibody, BOFS antibody, TFAP2 antibody, ap2 antibody, xap2 antibody, XAP-2 antibody, ap2tf antibody, tfap2 antibody, ap-2alpha antibody, tfap2alpha antibody, cb93 antibody, fb83f04 antibody, fc31a07 antibody, wu:fb83f04 antibody, wu:fc31a07 antibody, tfap2a-a antibody, tcfap2a antibody, ap2a antibody, AP2alpha antibody, Ap2 antibody, Ap2tf antibody, Tcfap2a antibody, AP2 antibody, transcription factor AP-2 alpha antibody, transcription factor AP-2 antibody, tto transcription factor AP-2 alpha antibody, to transcription factor AP-2 alpha L homeolog antibody, to transcription factor AP-2 alpha S homeolog antibody, Transcription factor AP-2 alpha antibody, transcription factor AP-2, alpha antibody, TFAP2A antibody, LOC100302602 antibody, tfap2a antibody, tfap2a.L antibody, tfap2a.S antibody, ap2a antibody, Tfap2a antibody
    Background
    TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM].
    Alias Symbols: AP-2, BOFS, AP2TF, TFAP2, AP-2alpha
    Protein Interaction Partner: MKRN3, GSTO2, KCTD15, SUMO1, HECW2, SP1, BAG3, RB1, UBC, DAB2, Fcho2, EPAS1, SRA1, EPS15, KCTD1, EPN1, SH3BP4, UBE2I, AURKA, BRCA1, DNMT3A, ELAVL1, SUMO4, SUMO2, NPM1, YY1, PPARG, EPN2, CITED4, LDLRAP1, CITED2, EP300, MAGI1, WWP2, WWP1, HIP1, CASP6, CASP3
    Protein Size: 437
    Molecular Weight
    48 kDa
    Gene ID
    7020
    NCBI Accession
    NM_003220, NP_003211
    UniProt
    P05549
    Pathways
    Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism
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