GTF2H2 antibody (Middle Region)

Catalog No. ABIN2792640

Product Details anti-GTF2H2 Antibody

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Horse, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2H2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HHLFPLDAFQ EIPLEEYNGE RFCYGCQGEL KDQHVYVCAV CQNVFCVDCD

Cross-Reactivity: Human

Predicted Reactivity: Dog: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against GTF2H2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GTF2H2

Application Details

Application Notes: WB Suggested Anti-GTF2H2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 395 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF2H2

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Alternative Name: GTF2H2 / BTF2P44 (GTF2H2 Products)

Synonyms: 44kDa antibody, BTF2 p44 antibody, BTF2-p44 antibody, Btf2p44 antibody, p44 antibody, BTF2 antibody, BTF2P44 antibody, T-BTF2P44 antibody, TFIIH antibody, general transcription factor II H, polypeptide 2 antibody, general transcription factor IIH subunit 2 antibody, general transcription factor IIH, polypeptide 2, 44kDa antibody, Gtf2h2 antibody, GTF2H2 antibody

Background: GTF2H2 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence hav
Alias Symbols: BTF2, BTF2P44, MGC102806, T-BTF2P44, TFIIH, p44
Protein Interaction Partner: UBC, CDK7, GTF2H5, GTF2H1, SRA1, GTF2H4, GTF2H3, UBD, COPS2, ERCC3, ERCC8, ERCC2, AR, MNAT1, CCNH,
Protein Size: 395

Molecular Weight: 44 kDa

Gene ID: 2966

NCBI Accession: NM_001515, NP_001506

UniProt: Q13888

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling