C-JUN antibody (Jun Proto-Oncogene) (N-Term)

Details for Product anti-JUN Antibody No. ABIN2792650, Supplier: Log in to see
Antigen
  • BSK
  • BSK/DJNK
  • Bsk
  • CG5680
  • D-JNK
  • D-junk
  • DBSK/JNK
  • DJNK
  • DJNK/bsk
  • Dmel\\CG5680
  • JNK
  • JNK/SAPK
  • Jnk
  • Junk
  • SAPKa
  • c-Jun
  • dJNK
  • jnk
  • Jun
  • AP-1
  • JUN
  • B230310J22Rik
  • p39
  • Junc
  • c-jun
  • AP1
  • fj36h07
  • wu:fj36h07
  • zgc:65863
  • CG2275
  • D-Jun
  • D-jun
  • D-jun/Jra
  • DJUN
  • DJun
  • Djun
  • Dmel\\CG2275
  • JRA
  • V
  • cJun
  • d-JRA
  • d-Jun
  • d-jun
  • dAP-1
  • dJRA
  • dJUN
  • dJra
  • dJun
  • djun
  • dm-Jun
  • jra
  • jun
  • l(2)46Ef
  • l(2)IA109
  • l(2R)IA109
  • jun oncogene
  • basket
  • C-JUN protein
  • c-Jun protein
  • c-jun transcription factor
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39)
  • Jun oncogene
  • jun proto-oncogene
  • Jun-related antigen
  • jun
  • bsk
  • C-JUN
  • Cdk5r2
  • Jun
  • JUN
  • Jra
Alternatives
anti-Mouse (Murine) C-JUN antibody for Western Blotting
Epitope
N-Term
91
75
52
47
46
46
44
30
30
20
19
17
15
15
15
15
10
8
8
7
7
6
6
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
879
552
497
70
59
49
44
43
38
33
24
20
14
9
8
5
5
3
2
2
2
1
1
Host
Rabbit
766
129
4
2
1
Clonality
Polyclonal
Conjugate
This C-JUN antibody is un-conjugated
19
18
18
11
10
10
8
8
7
7
7
7
7
7
7
7
7
1
1
1
1
1
1
1
1
1
1
1
1
Application
Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (IHC), Western Blotting (WB)
718
381
223
180
106
93
87
71
28
22
15
11
10
9
6
4
2
2
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human JUN
Sequence TAKMETTFYD DALNASFLPS ESGPYGYSNP KILKQSMTLN LADPVGSLKP
Cross-Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Predicted Reactivity Cow: 92%, Dog: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 92%, Sheep: 92%
Characteristics This is a rabbit polyclonal antibody against JUN. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name AP-1 / c-Jun (JUN Antibody Abstract)
Background JUN gene is the putative transforming gene of avian sarcoma virus 17. I JUN is highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. JUN gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AP1, c-Jun, AP-1
Protein Interaction Partner: PPP3CA, SP1, HDAC1, GSK3B, FOS, ABL1, MAPK8, RFWD2, CORO7, EP300, STRN4, MAPRE3, CREB3, PRRC2A, MDM2, SMAD2, HSP90AA1, HSPA8, ATF2, APP, APLP2, GOPC, BBS7, ETS1, CREBBP, CASP9, UBC, NCOR1, EPAS1, DDIT3, BATF2, BATF3, BATF, FOSL1, SMARCD3, CEBPG, CEBPE, AT
Protein Size: 331
Molecular Weight 36 kDa
Gene ID 3725
NCBI Accession NM_002228, NP_002219
UniProt P05412
Pathways MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor
Application Notes WB Suggested Anti-JUN Antibody Titration: 0.2-1 µg/mL
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 331 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Jun Proto-Oncogene (JUN) (N-Term) antibody (ABIN2792650) WB Suggested Anti-JUN Antibody Titration: 0.2-1 ug/ml
Positive Control: ...
Chromatin Immunoprecipitation (ChIP) image for anti-Jun Proto-Oncogene (JUN) (N-Term) antibody (ABIN2792650) Chromatin Immunoprecipitation (ChIP) Using JUN Antibody - N-terminal region (P100911_...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Jun Proto-Oncogene (JUN) (N-Term) antibody (ABIN2792650) Rabbit Anti-JUN Antibody ,Paraffin Embedded Tissue: Human alveolar cell
Cellul...
Product cited in: Russo, Pinsino, Costa, Bonaventura, Matranga, Zito: "The newly characterized Pl-jun is specifically expressed in skeletogenic cells of the Paracentrotus lividus sea urchin embryo." in: The FEBS journal, Vol. 281, Issue 17, pp. 3828-43, 2014 (PubMed).

Background publications Adiseshaiah, Li, Vaz, Kalvakolanu, Reddy: "ERK signaling regulates tumor promoter induced c-Jun recruitment at the Fra-1 promoter." in: Biochemical and biophysical research communications, Vol. 371, Issue 2, pp. 304-8, 2008 (PubMed).

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