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GTF2B antibody (N-Term)

GTF2B Reactivity: Human, Mouse, Dog, Zebrafish (Danio rerio), Horse, Guinea Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2792692
  • Target See all GTF2B Antibodies
    GTF2B (General Transcription Factor IIB (GTF2B))
    Binding Specificity
    • 15
    • 14
    • 11
    • 9
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 76
    • 29
    • 13
    • 11
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Human, Mouse, Dog, Zebrafish (Danio rerio), Horse, Guinea Pig, Rabbit
    Host
    • 61
    • 16
    Rabbit
    Clonality
    • 63
    • 14
    Polyclonal
    Conjugate
    • 44
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GTF2B antibody is un-conjugated
    Application
    • 62
    • 32
    • 13
    • 13
    • 12
    • 12
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    NLPRNIVDRT NNLFKQVYEQ KSLKGRANDA IASACLYIAC RQEGVPRTFK
    Cross-Reactivity
    Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
    Predicted Reactivity
    Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 92%
    Characteristics
    This is a rabbit polyclonal antibody against GTF2B. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2B
    Top Product
    Discover our top product GTF2B Primary Antibody
  • Application Notes
    WB Suggested Anti-GTF2B Antibody Titration: 4.0 µg/mL
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 316 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tubon, Tansey, Herr: "A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2863-74, (2004) (PubMed).

  • Target
    GTF2B (General Transcription Factor IIB (GTF2B))
    Alternative Name
    GTF2B (GTF2B Products)
    Synonyms
    CG5193 antibody, Dmel\\CG5193 antibody, TFIIB antibody, Tfiib antibody, TfllB antibody, dTFIIB antibody, dTfIIB antibody, dmTFIIB antibody, gtf2b antibody, tf2b antibody, tfiib antibody, XLTFIIB antibody, TF2B antibody, wu:fc44c11 antibody, zgc:66258 antibody, Transcription factor IIB antibody, transcription initiation factor iib antibody, transcription initiation factor IIB antibody, transcription initiation factor IIB 2 antibody, Transcription initiation factor IIB antibody, general transcription factor 2B S homeolog antibody, general transcription factor 2B L homeolog antibody, general transcription factor IIB antibody, TfIIB antibody, CNF01950 antibody, tfb antibody, CC1G_14689 antibody, HacjB3_18813 antibody, HALXA_RS07110 antibody, HALXA_RS16310 antibody, tf2b antibody, LOC100283348 antibody, gtf2b.S antibody, gtf2b.L antibody, GTF2B antibody, gtf2b antibody, Gtf2b antibody
    Background
    GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
    Alias Symbols: TF2B, TFIIB
    Protein Interaction Partner: DRAP1, TNIP1, UBC, FBXO25, HNF4A, TCEA1, GTF2F2, GTF2F1, DEPDC7, SLC22A2, RELA, POLR2C, JAK3, HMGCL, SMURF1, THRA, TBP, POLR2E, SRA1, LSM4, LSM5, CIITA, NXF1, POU3F2, EP300, PSMA3, POLR2J, ESR1, UL48, NR1D2, NCOR1, TAF9, REST, tat, SAP25, MKX, CTDP1, POLR
    Protein Size: 316
    Molecular Weight
    35 kDa
    Gene ID
    2959
    NCBI Accession
    NM_001514, NP_001505
    UniProt
    Q00403
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