PDX1 antibody (C-Term)
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- Target See all PDX1 Antibodies
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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Binding Specificity
- AA 186-215, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDX1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Purpose
- Rabbit Anti-Human IPF (C-term) Antibody
- Immunogen
- This IPF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the C-terminal region of human IPF.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PDX1 Primary Antibody
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- Application Notes
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Western Blot, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IF: 1:10-50Ipf Antibody (C-term) . IPF immunoreactivity is localized to Cytoplasm and Nucleus significantly. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2.0 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- Alternative Name
- IPF (PDX1 Products)
- Synonyms
- GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
- Background
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Target Description: IPF is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Gene Symbol: PDX1
- Molecular Weight
- 30771 Da
- Gene ID
- 3651
- UniProt
- P52945
- Pathways
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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