GSG2 antibody (Center)

Catalog No. ABIN2793339

Product Details anti-GSG2 Antibody

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSG2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Purpose: Rabbit Anti-Human Haspin GSG2 (Center) Antibody

Immunogen: This Haspin GSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323~352 amino acids from the central region of human haspin.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Haspin Antibody (R330) .
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for GSG2

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Alternative Name: Haspin GSG2 (GSG2 Products)

Synonyms: BcDNA:LD07633 antibody, CG40080 antibody, Dmel\\CG40080 antibody, haspin antibody, NV16901 antibody, HASPIN antibody, Haspin antibody, putative serine/threonine-protein kinase haspin homolog antibody, histone H3 associated protein kinase antibody, CG40080 gene product from transcript CG40080-RA antibody, uncharacterized LOC100122327 antibody, LOC552287 antibody, HASPIN antibody, Haspin antibody, LOC100122327 antibody

Background:

Target Description: Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Mitotic phosphorylation of H3 Thr 3 occurs in prophase and dephosphorylation during anaphase. Haspin, a dual serine/threonine kinase, plays an important role in regulation of chromosome and spindle function during mitosis and meiosis via its function in phosphorylation of the threonine residue in the third position of histone 3 (Thr3).

Gene Symbol: GSG2

Molecular Weight: 88495 Da

Gene ID: 83903

UniProt: Q8TF76