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CDK11 antibody

CDK11B Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1944862
  • Target See all CDK11 (CDK11B) Antibodies
    CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))
    Reactivity
    • 35
    • 15
    • 3
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 36
    Rabbit
    Clonality
    • 36
    Polyclonal
    Conjugate
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK11 antibody is un-conjugated
    Application
    • 25
    • 13
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Isotype
    IgG
    Top Product
    Discover our top product CDK11B Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Storage
    4 °C,-20 °C
  • Gururajan, Lahti, Grenet, Easton, Gruber, Ambros, Kidd: "Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2." in: Genome research, Vol. 8, Issue 9, pp. 929-39, (1998) (PubMed).

    Xiang, Lahti, Grenet, Easton, Kidd: "Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms." in: The Journal of biological chemistry, Vol. 269, Issue 22, pp. 15786-94, (1994) (PubMed).

    Eipers, Lahti, Kidd: "Structure and expression of the human p58clk-1 protein kinase chromosomal gene." in: Genomics, Vol. 13, Issue 3, pp. 613-21, (1992) (PubMed).

    Lake, de la Cruz, Ferreira, Morel, Simpson: "Evolution of parasitism: kinetoplastid protozoan history reconstructed from mitochondrial rRNA gene sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 6, pp. 2612, (1991) (PubMed).

    Bunnell, Heath, Adams, Lahti, Kidd: "Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 19, pp. 7467-71, (1990) (PubMed).

  • Target
    CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))
    Alternative Name
    CDC2L1 (CDK11B Products)
    Synonyms
    CDC2L1 antibody, CDK11 antibody, CDK11-p110 antibody, CDK11-p46 antibody, CDK11-p58 antibody, CLK-1 antibody, PK58 antibody, p58 antibody, p58CDC2L1 antibody, p58CLK-1 antibody, AA989746 antibody, Cdc11b antibody, Cdc2l1 antibody, Cdc2l2 antibody, Cdk11 antibody, CDC2L2 antibody, CDK11B antibody, cdc2l1 antibody, im:7142267 antibody, zgc:101589 antibody, cdc2l2 antibody, cdk11 antibody, cdk11-p110 antibody, cdk11-p46 antibody, cdk11-p58 antibody, cdk11b antibody, clk-1 antibody, p58cdc2l1 antibody, p58clk-1 antibody, pk58 antibody, cyclin dependent kinase 11B antibody, cyclin-dependent kinase 11B antibody, cyclin-dependent kinase 11B S homeolog antibody, CDK11B antibody, Cdk11b antibody, LOC489591 antibody, cdk11b antibody, cdk11b.S antibody
    Background
    Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
    Molecular Weight
    92707 Da
    Gene ID
    984
    UniProt
    P21127
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, M Phase
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