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MAPK10 antibody (AA 251-360) (Alexa Fluor 594)

MAPK10 Reactivity: Mouse, Rat IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 594
Catalog No. ABIN2803475
  • Target See all MAPK10 Antibodies
    MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
    Binding Specificity
    • 14
    • 10
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-360
    Reactivity
    • 61
    • 49
    • 32
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 63
    • 8
    • 3
    Rabbit
    Clonality
    • 57
    • 19
    Polyclonal
    Conjugate
    • 32
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPK10 antibody is conjugated to Alexa Fluor 594
    Application
    • 45
    • 38
    • 25
    • 12
    • 12
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human JNK3/MAPK10
    Isotype
    IgG
    Top Product
    Discover our top product MAPK10 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
    Alternative Name
    JNK3 (MAPK10 Products)
    Synonyms
    MAPK10 antibody, zgc:123234 antibody, DKFZp459H0638 antibody, Jnk3 antibody, SAPKC antibody, SAPb antibody, Serk2 antibody, JNK3 antibody, JNK3A antibody, PRKM10 antibody, SAPK1b antibody, p493F12 antibody, p54bSAPK antibody, C230008H04Rik antibody, JNK3B1 antibody, JNK3B2 antibody, SAPK(beta) antibody, ATMPK10 antibody, MAP kinase 10 antibody, mitogen-activated protein kinase 8 S homeolog antibody, mitogen-activated protein kinase 10 antibody, mitogen activated protein kinase 10 antibody, MAP kinase 10 antibody, mapk8.S antibody, MAPK10 antibody, mapk10 antibody, Mapk10 antibody, MPK10 antibody
    Background

    Synonyms: cJun N terminal kinase 3, MAP kinase p49 3F12, Stress activated protein kinase JNK3, c Jun kinase 3, JNK3, JNK3A, MAP kinase, mitogen activated protein kinase 10, p493F12, p54bSAPK, PRKM10, protein kinase mitogen activated 10 , stress activated protein kinase beta.

    Background: MAPK10 (JNK3) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuron-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 (CDK5) can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Gene ID
    5602
    Pathways
    MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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