REC8 antibody (AA 22-120) (Alexa Fluor 594)

Catalog No. ABIN2805874

Product Details anti-REC8 Antibody (Alexa Fluor 594)

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Binding Specificity: AA 22-120

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REC8 antibody is conjugated to Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human REC8

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for REC8

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Alternative Name: REC8 (REC8 Products)

Synonyms: Rec8L1 antibody, mrec antibody, HR21spB antibody, REC8L1 antibody, Rec8p antibody, REC8 meiotic recombination protein antibody, REC8 homolog (yeast) antibody, REC8 antibody, Rec8 antibody

Background:

Synonyms: Rec8p, REC8L1, HR21spB, Meiotic recombination protein REC8 homolog, Cohesin Rec8p, REC8

Background: Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).

Gene ID: 9985

UniProt: O95072