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RanBP3 antibody (AA 441-540) (Alexa Fluor 350)

RANBP3 Reactivity: Mouse, Rat WB, IF (p), IF (cc) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN2809134
  • Target See all RanBP3 (RANBP3) Antibodies
    RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))
    Binding Specificity
    • 14
    • 9
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 441-540
    Reactivity
    • 27
    • 17
    • 15
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 39
    • 2
    Rabbit
    Clonality
    • 38
    • 3
    Polyclonal
    Conjugate
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RanBP3 antibody is conjugated to Alexa Fluor 350
    Application
    • 38
    • 19
    • 14
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Pig,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RanBP3
    Isotype
    IgG
    Top Product
    Discover our top product RANBP3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))
    Alternative Name
    RanBP3 (RANBP3 Products)
    Synonyms
    2610024N24Rik antibody, AA408221 antibody, ranbp3 antibody, MGC79798 antibody, zgc:63485 antibody, RAN binding protein 3 antibody, RAN binding protein 3 L homeolog antibody, RAN binding protein 3a antibody, RANBP3 antibody, Ranbp3 antibody, ranbp3.L antibody, ranbp3 antibody, ranbp3a antibody
    Background

    Synonyms: Ran-binding protein 3, RanBP3

    Background: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.

    Gene ID
    8498
    UniProt
    Q9H6Z4
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