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ALOXE3 antibody (AA 141-240) (Alexa Fluor 594)

ALOXE3 Reactivity: Human IF (p), IF (cc) Host: Rabbit Polyclonal Alexa Fluor 594
Catalog No. ABIN2809626
  • Target See all ALOXE3 Antibodies
    ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 141-240
    Reactivity
    • 39
    • 8
    Human
    Host
    • 37
    • 2
    Rabbit
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALOXE3 antibody is conjugated to Alexa Fluor 594
    Application
    • 24
    • 18
    • 12
    • 12
    • 5
    • 4
    • 3
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ALOXE3
    Isotype
    IgG
    Top Product
    Discover our top product ALOXE3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))
    Alternative Name
    ALOXE3 (ALOXE3 Products)
    Synonyms
    e-lox antibody, elox3 antibody, ARCI3 antibody, E-LOX antibody, eLOX3 antibody, e-LOX-3 antibody, ALOX15B antibody, arachidonate lipoxygenase 3 antibody, arachidonate lipoxygenase 3 L homeolog antibody, arachidonate 15-lipoxygenase, type B antibody, ALOXE3 antibody, aloxe3.L antibody, aloxe3 antibody, Aloxe3 antibody, ALOX15B antibody
    Background

    Synonyms: ALOXE3, Arachidonate lipoxygenase 3, e LOX 3, E LOX, e-LOX-3, eLOX3, Epidermal lipoxygenase, Epidermis-type lipoxygenase 3, Lipoxygenase 3, LOXE3_HUMAN.

    Background: Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known.Tissue specificity:Predominantly expressed in skin.Involvement in diseaseDefects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE). NCIE is a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affected individuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membrane subsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than in lamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. In contrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severely affected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume.

    Gene ID
    59344
    Pathways
    Cell-Cell Junction Organization
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