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HOOK1 antibody (AA 551-650) (Alexa Fluor 594)

HOOK1 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 594
Catalog No. ABIN2814452
  • Target See all HOOK1 Antibodies
    HOOK1 (Hook Homolog 1 (HOOK1))
    Binding Specificity
    • 14
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 551-650
    Reactivity
    • 34
    • 22
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 44
    • 4
    Rabbit
    Clonality
    • 46
    • 2
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HOOK1 antibody is conjugated to Alexa Fluor 594
    Application
    • 43
    • 24
    • 12
    • 12
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HOOK1
    Isotype
    IgG
    Top Product
    Discover our top product HOOK1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HOOK1 (Hook Homolog 1 (HOOK1))
    Alternative Name
    HOOK1 (HOOK1 Products)
    Synonyms
    si:dkey-183n20.14 antibody, A930033L17Rik antibody, azh antibody, HK1 antibody, HOOK1 antibody, hook microtubule tethering protein 1 antibody, hook microtubule-tethering protein 1 antibody, HOOK1 antibody, hook1 antibody, Hook1 antibody
    Background

    Synonyms: A930033L17Rik, Abnormal spermatozoon head shape, azh, h-hook1, hHK1, HK1, HOOK 1, Hook homolog 1 Drosophila, Hook1, HOOK1_HUMAN, MGC10642, OTTHUMP00000010548, OTTMUSP00000008480, Protein Hook homolog 1, RP23-80B16.4.

    Background: Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.

    Gene ID
    51361
    Pathways
    SARS-CoV-2 Protein Interactome
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