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LATS2 antibody (AA 228-258)

LATS2 Reactivity: Human IHC (p) Host: Rabbit Polyclonal RB3032 unconjugated
Catalog No. ABIN2837939
  • Target See all LATS2 Antibodies
    LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
    Binding Specificity
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 228-258
    Reactivity
    • 64
    • 56
    • 15
    • 4
    Human
    Host
    • 72
    • 2
    Rabbit
    Clonality
    • 72
    • 2
    Polyclonal
    Conjugate
    • 21
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    This LATS2 antibody is un-conjugated
    Application
    • 32
    • 31
    • 13
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This LATS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-258 amino acids from the Central region of human LATS2.
    Clone
    RB3032
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LATS2 Primary Antibody
  • Application Notes
    IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Yamashita, Yamamoto, Mimori, Nishida, Takahashi, Haraguchi, Tanaka, Shibata, Sekimoto, Ishii, Doki, Mori: "MicroRNA-372 is associated with poor prognosis in colorectal cancer." in: Oncology, Vol. 82, Issue 4, pp. 205-12, (2012) (PubMed).

  • Target
    LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
    Alternative Name
    LATS2 (LATS2 Products)
    Synonyms
    4932411G09Rik antibody, AV277261 antibody, AW228608 antibody, KPM antibody, lats2 antibody, large tumor suppressor kinase 2 antibody, large tumor suppressor 2 antibody, LATS2 antibody, Lats2 antibody, lats2 antibody
    Background
    LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. This protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
    Molecular Weight
    120136
    Gene ID
    26524
    NCBI Accession
    NP_055387
    UniProt
    Q9NRM7
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