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PRKAA2 antibody
PRKAA2
Reactivity: Human
WB, IF
Host: Mouse
Monoclonal
206CT5-4-2
unconjugated
Product Details anti-PRKAA2 Antibody
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Target
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PRKAA2
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
Reactivity
All reactivities for PRKAA2 antibodies
Human
Host
All hosts for PRKAA2 antibodies
Mouse
Clonality
All clonalities for PRKAA2 antibodies
Monoclonal
Conjugate
All conjugates for PRKAA2 antibodies
This PRKAA2 antibody is un-conjugated
Application
All applications for PRKAA2 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
Clone
206CT5-4-2
Isotype
IgG2a kappa
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Discover our top product PRKAA2 Primary Antibody
Alternatives
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anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 351-450) antibody
PRKAA2
Reactivity: Human, Mouse, Rat
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IF: 1:10~50. WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for PRKAA2
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Target
PRKAA2
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
Alternative Name
PRKAA2 (PRKAA2 Products )
Synonyms
AMPK antibody, AMPK2 antibody, AMPKa2 antibody, PRKAA antibody, Ampk antibody, Ampka2 antibody, 2310008I11Rik antibody, A830082D05 antibody, AMPKalpha2 antibody, AMPKA2 antibody, ampk antibody, ampk2 antibody, prkaa antibody, prkaa1 antibody, PRKAA2 antibody, protein kinase AMP-activated catalytic subunit alpha 2 antibody, protein kinase, AMP-activated, alpha 2 catalytic subunit antibody, protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog antibody, PRKAA2 antibody, Prkaa2 antibody, prkaa2.S antibody, prkaa2 antibody
Background
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Molecular Weight
62320
Gene ID
5563
NCBI Accession
NP_006243
UniProt
P54646
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Chromatin Binding , Regulation of Carbohydrate Metabolic Process , Warburg Effect
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