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SCNN1B antibody (AA 306-332)

SCNN1B Reactivity: Human WB Host: Rabbit Polyclonal RB42043 unconjugated
Catalog No. ABIN2838920
  • Target See all SCNN1B Antibodies
    SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))
    Binding Specificity
    • 43
    • 24
    • 22
    • 20
    • 15
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 306-332
    Reactivity
    • 96
    • 66
    • 52
    • 12
    • 12
    • 11
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 95
    • 45
    Rabbit
    Clonality
    • 97
    • 43
    Polyclonal
    Conjugate
    • 30
    • 10
    • 10
    • 9
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This SCNN1B antibody is un-conjugated
    Application
    • 125
    • 39
    • 39
    • 31
    • 27
    • 9
    • 7
    • 5
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SCNN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-332 amino acids from the Central region of human SCNN1B.
    Clone
    RB42043
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SCNN1B Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Song, Wei, Zhou, Lazrak, Liu, Londino, Squadrito, Matalon: "Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9716-28, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Azad, Rauh, Vermeulen, Jaspers, Korbmacher, Boissier, Bassinet, Fichou, des Georges, Stanke, De Boeck, Dupont, Balascáková, Hjelte, Lebecque: "Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease." in: Human mutation, Vol. 30, Issue 7, pp. 1093-103, (2009) (PubMed).

  • Target
    SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))
    Alternative Name
    SCNN1B (SCNN1B Products)
    Synonyms
    BESC1 antibody, ENaCb antibody, ENaCbeta antibody, SCNEB antibody, RNENACB antibody, besc1 antibody, betaxENaC antibody, enacb antibody, enacbeta antibody, scnn1b antibody, beta-ENaC antibody, scneb antibody, SCNN1B antibody, BETA-ENAC antibody, sodium channel epithelial 1 beta subunit antibody, sodium channel, non voltage gated 1 beta subunit L homeolog antibody, sodium channel, non voltage gated 1 beta subunit antibody, sodium channel, nonvoltage-gated 1 beta antibody, sodium channel, non voltage gated 1 beta subunit S homeolog antibody, SCNN1B antibody, Scnn1b antibody, scnn1b.L antibody, scnn1b antibody, scnn1b.S antibody
    Background
    Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.
    Molecular Weight
    72659
    NCBI Accession
    NP_000327
    UniProt
    P51168
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