SEMA6A antibody (N-Term)

Catalog No. ABIN2839369

Product Details anti-SEMA6A Antibody

Target: SEMA6A (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A))

Binding Specificity: AA 29-57, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEMA6A antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEMA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human SEMA6A.

Clone: RB21218

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SEMA6A

Target: SEMA6A (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A))

Alternative Name: SEMA6A (SEMA6A Products)

Synonyms: fj46c12 antibody, wu:fj46c12 antibody, zgc:66106 antibody, SEMA6A antibody, HT018 antibody, SEMA antibody, SEMA6A1 antibody, SEMAQ antibody, VIA antibody, 9330158E07 antibody, A730020P05Rik antibody, AI851735 antibody, Sema6A-1 antibody, Semaq antibody, VIa antibody, b2b997Clo antibody, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A antibody, semaphorin 6A antibody, sema6a antibody, SEMA6A antibody, Sema6a antibody

Background: SEMA6A belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. However, the length of the cytoplasmic tail, which includes an EVL-binding site in SEMA6A and an Src-binding site in SEMA6B, suggests that these semaphorins may also function as receptors. SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection. SEMA6A directly links the Ena/VASP and the semaphorin protein families since the SEMA6A protein is capable of selective binding to the protein EVL (Ena/VASP-like protein).

Molecular Weight: 114395

Gene ID: 57556

NCBI Accession: NP_065847

UniProt: Q9H2E6