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LGR5 antibody (N-Term)

LGR5 Reactivity: Mouse WB Host: Rabbit Polyclonal RB14764 unconjugated
Catalog No. ABIN2839371
  • Target See all LGR5 Antibodies
    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
    Binding Specificity
    • 16
    • 15
    • 11
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 238-270, N-Term
    Reactivity
    • 105
    • 57
    • 49
    • 1
    • 1
    Mouse
    Host
    • 93
    • 13
    Rabbit
    Clonality
    • 82
    • 24
    Polyclonal
    Conjugate
    • 50
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGR5 antibody is un-conjugated
    Application
    • 79
    • 39
    • 22
    • 20
    • 17
    • 17
    • 14
    • 13
    • 9
    • 7
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    H
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This LGR5/GPR49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-270 amino acids from the N-terminal region of human LGR5/GPR49.
    Clone
    RB14764
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LGR5 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Usui, Sakurai, Enjoji, Kawasaki, Umata, Ohama, Fujiwara, Yabe, Tsuji, Yamawaki, Hazama, Takenouchi, Nakajima, Tsunedomi, Suzuki, Nagano, Sato: "Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment." in: Stem cells international, Vol. 2016, pp. 7053872, (2017) (PubMed).

    Fender, Nutter, Bertrand, Sigounas: "Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer." in: Journal of cellular biochemistry, (2015) (PubMed).

    Jardé, Kass, Staples, Lescesen, Carne, Oliva, McMurrick, Abud: "ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138336, (2015) (PubMed).

    Kanwar, Yu, Nautiyal, Patel, Majumdar: "The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres." in: Molecular cancer, Vol. 9, pp. 212, (2010) (PubMed).

  • Target
    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
    Alternative Name
    LGR5/GPR49 (LGR5 Products)
    Synonyms
    lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody
    Background
    LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.
    Molecular Weight
    99998
    Gene ID
    8549
    NCBI Accession
    NP_001264155, NP_003658
    UniProt
    O75473
    Pathways
    WNT Signaling
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