GADD45A antibody (N-Term)

Catalog No. ABIN2839407

Product Details anti-GADD45A Antibody

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GADD45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GADD45A.

Clone: RB16520

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Alternative Name: GADD45A (GADD45A Products)

Synonyms: MGC53491 antibody, zgc:91795 antibody, gadd45a antibody, GADD45A antibody, ddit1 antibody, gadd45 antibody, GADD45 antibody, AA545191 antibody, Ddit1 antibody, DDIT1 antibody, Gadd45 antibody, growth arrest and DNA damage inducible alpha L homeolog antibody, growth arrest and DNA-damage-inducible, alpha, b antibody, growth arrest and DNA damage inducible alpha antibody, growth arrest and DNA damage-inducible protein 45 antibody, growth arrest and DNA-damage-inducible 45 alpha antibody, growth arrest and DNA-damage-inducible, alpha antibody, gadd45a.L antibody, gadd45ab antibody, GADD45A antibody, gadd45a antibody, GADD45 antibody, Gadd45a antibody

Background: GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45A gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.

Molecular Weight: 18336

Gene ID: 1647

NCBI Accession: NP_001186670, NP_001186671, NP_001915

UniProt: P24522

Pathways: p53 Signaling, Cell Division Cycle